Description

1-(4-Bromophenyl)-3-[(4-Fluorophenyl)Sulfonyl]-1-Propanone is a high-purity, specialized organic intermediate featuring a unique sulfonyl ketone structure with bromo and fluoro substituents. This compound is valued for its role as a critical building block in advanced pharmaceutical and agrochemical synthesis, enabling the development of novel active ingredients. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors or other small-molecule therapeutics.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, fungicides, or insecticides, leveraging the bioactivity of its aryl bromo and fluoro groups.
• Material Science Research: Used in the development of specialty polymers, liquid crystals, or organic electronic materials due to its rigid, functionalized aromatic core.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for biochemical and pharmacological studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	1-(4-Bromophenyl)-3-[(4-Fluorophenyl)Sulfonyl]-1-Propanone
CAS No.	868256-27-3
Molecular Formula	C15H12BrFO3S
Molecular Weight	371.22 g/mol
Synonyms	3-[(4-Fluorophenyl)sulfonyl]-1-(4-bromophenyl)propan-1-one; 1-Propanone, 1-(4-bromophenyl)-3-[(4-fluorophenyl)sulfonyl]-; 4-Bromo-ω-[(4-fluorophenyl)sulfonyl]acetophenone; 1-(4-Bromophenyl)-3-(4-fluorophenylsulfonyl)propan-1-one; 868256-27-3; AKOS005258915
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromophenyl)-3-[(4-Fluorophenyl)Sulfonyl]-1-Propanone is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.