Description

1-(4-Fluorophenyl)-3-[(2,4,5,6-Pentamethylbenzyl)Sulfonyl]-1-Propanone is a high-value, synthetically versatile chemical building block. This compound is engineered to serve as a critical intermediate in advanced organic synthesis, offering a unique combination of a fluorinated aromatic ring and a pentamethylbenzyl sulfonyl group. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its fluorinated aromatic structure.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic electronic materials.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(4-Fluorophenyl)-3-[(2,4,5,6-Pentamethylbenzyl)Sulfonyl]-1-Propanone
CAS No.	868255-95-2
Molecular Formula	C21H23FO3S
Molecular Weight	374.47 g/mol
Synonyms	1-Propanone, 1-(4-fluorophenyl)-3-[(2,4,5,6-pentamethylbenzyl)sulfonyl]-; 3-[(2,4,5,6-Pentamethylbenzyl)sulfonyl]-1-(4-fluorophenyl)propan-1-one; 4-Fluoro-β-(2,4,5,6-pentamethylbenzylsulfonyl)propiophenone; 1-(4-Fluorophenyl)-3-(pentamethylbenzylsulfonyl)propan-1-one; Fluorophenyl pentamethylbenzylsulfonyl propanone; FPPBSP; PMB Sulfonyl Fluorophenyl Propanone Intermediate
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-3-[(2,4,5,6-Pentamethylbenzyl)Sulfonyl]-1-Propanone adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and process development. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.