Description

1-(4-Methoxyphenyl)-3-(2,3,4-Trifluoroanilino)-1-Propanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct trifluoromethyl and methoxyphenyl functional groups. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated molecules for enhanced metabolic stability and bioavailability. Pharmaceutical R&D and fine chemical manufacturers need this precise building block to develop next-generation drugs targeting central nervous system disorders, anti-inflammatory applications, and other specialized treatments.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel fluorinated Active Pharmaceutical Ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fluorinated Compound Synthesis: Serves as a precursor for creating complex molecules with trifluoromethyl and anilino moieties.
• Agrochemical Research: Potential intermediate in the development of advanced pesticides and herbicides leveraging fluorine chemistry.
• Material Science: Exploration of applications in organic electronic materials and specialty polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services.

Basic Information

Product Name	1-(4-Methoxyphenyl)-3-(2,3,4-Trifluoroanilino)-1-Propanone
CAS No.	868255-55-4
Molecular Formula	C16H13F3NO2
Molecular Weight	308.28 g/mol
Synonyms	1-Propanone, 1-(4-methoxyphenyl)-3-[(2,3,4-trifluorophenyl)amino]-; 3-[(2,3,4-Trifluorophenyl)amino]-1-(4-methoxyphenyl)-1-propanone; 1-(4-Methoxyphenyl)-3-[(2,3,4-trifluorophenyl)amino]propan-1-one; 868255-55-4; 3-(2,3,4-Trifluoroanilino)-1-(4-methoxyphenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 1-(4-Methoxyphenyl)-3-(2,3,4-Trifluoroanilino)-1-Propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.