Description

Quinoline, 2-Phenyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is a high-value, functionalized quinoline derivative containing a pinacol boronate ester group, making it a crucial building block in modern synthetic chemistry. This compound matters because it serves as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those containing complex quinoline and biphenyl scaffolds for oncology, antiviral, and anti-inflammatory applications.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection products, leveraging the Suzuki coupling to introduce diverse aromatic moieties.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emitting layer hosts in display and lighting technologies.
• Ligand and Catalyst Development: Utilized in the preparation of novel nitrogen-containing ligands for transition metal catalysis.
• Polymer and Material Science: Incorporated into conjugated polymers and small molecules for organic photovoltaics (OPVs) and field-effect transistors (OFETs).
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of fluorescent or bioactive probes.

Basic Information

Item	Details
Product Name	Quinoline, 2-Phenyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-
CAS No.	867164-54-3
Molecular Formula	C21H22BNO2
Molecular Weight	331.22 g/mol
Synonyms	2-Phenyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline; 7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylquinoline; 2-Phenylquinoline-7-boronic acid pinacol ester; Quinoline-7-boronic acid, 2-phenyl-, pinacol ester; (2-Phenylquinolin-7-yl)boronic acid pinacol ester; B-(2-Phenyl-7-quinolinyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Quinoline, 2-Phenyl-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)- is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality systems are designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent hydrolysis of the boronate ester.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.