Description

4-[3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Propyl]Benzaldehyde is a high-purity, organosilicon-protected benzaldehyde derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in the tert-butyldimethylsilyl (TBDMS) protecting group, which provides exceptional stability for sensitive aldehyde functionalities during multi-step synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, where it is used to construct complex molecular architectures for active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating aldehydes under protective schemes.
• Peptide & Nucleotide Chemistry: Used in the protection of aldehyde groups during the solid-phase synthesis of complex biomolecules.
• Liquid Crystal & OLED Material Synthesis: Serves as a precursor for creating advanced organic electronic materials with specific optical properties.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts for enantioselective reactions.
• Polymer & Dendrimer Functionalization: Used to introduce aldehyde handles onto polymer backbones for further cross-linking or conjugation.
• Agrochemical Research: Intermediate in the development of new plant protection agents and growth regulators.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and protecting group chemistry.

Basic Information

Item	Details
Product Name	4-[3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Propyl]Benzaldehyde
CAS No.	866815-84-1
Molecular Formula	C16H26O2Si
Molecular Weight	278.47 g/mol
Synonyms	4-(3-((tert-Butyldimethylsilyl)oxy)propyl)benzaldehyde; 4-[3-[(tert-Butyldimethylsilyl)oxy]propyl]benzaldehyde; p-[3-(tert-Butyldimethylsiloxy)propyl]benzaldehyde; TBDMS-protected 4-(3-Hydroxypropyl)benzaldehyde; 4-(3-Hydroxypropyl)benzaldehyde TBDMS ether; (4-Formylphenyl)propyl tert-butyldimethylsilyl ether; Benzaldehyde, 4-[3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]propyl]-
EINECS	Contact for details

Quality Control

Our 4-[3-[[(1,1-Dimethylethyl)Dimethylsilyl]Oxy]Propyl]Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly sealed to protect the product from moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.