Description

2'-Fluoro-4'-Nitroacetophenone is a specialized aromatic ketone building block characterized by its strategically positioned fluorine and nitro substituents. This compound is valued for its role as a key synthetic intermediate in the development of complex, high-value molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by research institutions and industrial manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and advanced crop protection agents.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, including potential kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Serves as a building block for developing novel herbicides, fungicides, and insecticides that leverage the fluorine atom for enhanced biological activity and metabolic stability.
• Material Science: Used in the research and development of advanced organic materials, such as liquid crystals and specialty polymers, where its molecular structure can influence material properties.
• Chemical Synthesis: Acts as a versatile substrate for various organic transformations, including nucleophilic aromatic substitution (SNAr) and reduction reactions, to create more complex fluorinated compounds.

Basic Information

Product Name	2'-Fluoro-4'-Nitroacetophenone
CAS No.	866579-96-6
Molecular Formula	C8H6FNO3
Molecular Weight	183.14 g/mol
Synonyms	1-(2-Fluoro-4-nitrophenyl)ethan-1-one; 2-Fluoro-4-nitroacetophenone; 2'-Fluoro-4'-nitroacetophenone; 1-Acetyl-2-fluoro-4-nitrobenzene; 2-Fluoro-4-nitroacetylbenzene; 4-Nitro-2-fluoroacetophenone; Ethanone, 1-(2-fluoro-4-nitrophenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-4'-Nitroacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the stringent requirements for research and development applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.