Description

1-(2-Phenoxyethyl)-3-[3-(Trifluoromethyl)Phenyl]Tetrahydro-2H-Imidazol-2-One is a high-value, specialized heterocyclic compound featuring a tetrahydroimidazol-2-one core substituted with phenoxyethyl and trifluoromethylphenyl groups. This structure makes it a critical advanced pharmaceutical intermediate for the synthesis of novel active ingredients, particularly in therapeutic areas requiring targeted bioactivity. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel small-molecule drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging the stability imparted by the trifluoromethyl group.
• Chemical Biology Probe Synthesis: Serves as a core scaffold for creating molecular probes to study biological pathways and protein interactions.
• Material Science Precursor: Potential use in synthesizing specialty polymers or ligands for advanced materials and catalysts.
• Contract Research & Development (CRO/CMO): Supplied to research organizations for custom synthesis and process development projects.

Basic Information

Product Name	1-(2-Phenoxyethyl)-3-[3-(Trifluoromethyl)Phenyl]Tetrahydro-2H-Imidazol-2-One
CAS No.	866040-40-6
Molecular Formula	C18H17F3N2O2
Molecular Weight	350.34 g/mol
Synonyms	1-(2-Phenoxyethyl)-3-[3-(trifluoromethyl)phenyl]-2-imidazolidinone; 3-[3-(Trifluoromethyl)phenyl]-1-(2-phenoxyethyl)tetrahydro-2H-imidazol-2-one; 2H-Imidazol-2-one, 1-(2-phenoxyethyl)-3-[3-(trifluoromethyl)phenyl]tetrahydro-; 866040-40-6; UNII-6J2H5Q8W7F; 6J2H5Q8W7F
EINECS	Contact for details

Quality Control

Our production of 1-(2-Phenoxyethyl)-3-[3-(Trifluoromethyl)Phenyl]Tetrahydro-2H-Imidazol-2-One adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.