Description

2'-Fluoro-3'-Methylacetophenone is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its value lies in the strategic placement of fluorine and methyl substituents, which are crucial for modulating the electronic and steric properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display technologies.
• Advanced Organic Synthesis: Employed in cross-coupling reactions, carbonyl chemistry, and as a precursor for heterocyclic compounds like benzofurans and indoles.
• Chemical Research & Development: Essential for academic and industrial R&D labs exploring new fluorination methodologies and structure-activity relationships.
• Fine Chemical Production: Acts as a specialized intermediate in the custom synthesis of complex, high-value fine chemicals for various industrial applications.

Basic Information

Product Name	2'-Fluoro-3'-Methylacetophenone
CAS No.	865664-05-7
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(2-Fluoro-3-methylphenyl)ethanone; 2-Fluoro-3-methylacetophenone; 2'-Fluoro-3'-methylacetophenone; 1-Acetyl-2-fluoro-3-methylbenzene; 2-Fluoro-3-methyl-1-acetylbenzene; 3-Methyl-2-fluoroacetophenone; Ethanone, 1-(2-fluoro-3-methylphenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Fluro-3'-Methylacetophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.