Description

(3-Fluorooxetan-3-Yl)Methanol is a high-value fluorinated oxetane derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive oxetane ring and a hydroxymethyl group, makes it an essential precursor for introducing fluorinated motifs into complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and materials science industries to create novel compounds with enhanced properties.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated active pharmaceutical ingredients (APIs), potentially improving metabolic stability and bioavailability.
• Agrochemical Research: Used in synthesizing novel fluorinated pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental persistence.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent for creating specialty fluorinated polymers with unique surface, thermal, or chemical resistance properties.
• Liquid Crystal & OLED Materials: A building block for fluorinated components in electronic display materials, influencing dielectric anisotropy and stability.
• Prodrug & Linker Chemistry: The oxetane and alcohol functionalities are useful in designing biodegradable linkers and prodrug systems for targeted drug delivery.
• Chemical Biology & Probe Development: Employed to synthesize fluorinated probes and tags for imaging and studying biological systems.

Basic Information

Product Name	(3-Fluorooxetan-3-Yl)Methanol
CAS No.	865451-85-0
Molecular Formula	C4H7FO2
Molecular Weight	106.10 g/mol
Synonyms	3-(Hydroxymethyl)-3-fluorooxetane; 3-Fluoro-3-(hydroxymethyl)oxetane; (3-Fluorooxetan-3-yl)methanol; 3-Fluorooxetane-3-methanol; 865451-85-0; 3-Fluoro-3-oxetanemethanol; Oxetane, 3-(hydroxymethyl)-3-fluoro-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated building blocks. Production follows current Good Manufacturing Practice (cGMP) principles where applicable, ensuring batch-to-batch consistency and traceability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced analytical techniques (NMR, HPLC, GC). Our quality system is designed to meet the exacting standards of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. For long-term storage, we recommend keeping the material under an inert atmosphere (e.g., nitrogen or argon) at temperatures between 2°C and 8°C to maintain optimal stability. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.