Description

1-(5-Bromo-2-Fluorophenyl)Propan-1-One is a high-purity fluorinated and brominated aromatic ketone building block of significant synthetic utility. This compound is valued for its role as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo-fluoro substitution pattern can enhance biological activity and metabolic stability.
• Material Science: Serves as a precursor for the synthesis of specialized polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a substrate for further functionalization to create diverse chemical libraries for screening.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and contract research organizations (CROs).

Basic Information

Product Name	1-(5-Bromo-2-Fluorophenyl)Propan-1-One
CAS No.	864774-65-2
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	1-Propanone, 1-(5-bromo-2-fluorophenyl)-; 5'-Bromo-2'-fluoropropiophenone; 1-(5-Bromo-2-fluorophenyl)-1-propanone; 2-Fluoro-5-bromopropiophenone; 5-Bromo-2-fluoropropiophenone; Propiophenone, 5-bromo-2-fluoro-; 864774-65-2
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-2-Fluorophenyl)Propan-1-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.