Description

Phenoxyphenyl-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing biaryl structures found in active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides requiring specific phenyl-ether linkages.
• Material Science: Employed in the synthesis of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand Synthesis: Serves as a starting material for creating sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology: Utilized in probe and sensor development due to its reactivity and the pinacol protection's stability.
• Custom Synthesis: A versatile reagent for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis.

Basic Information

Product Name	Phenoxyphenyl-3-Boronic Acid Pinacol Ester
CAS No.	864772-18-9
Molecular Formula	C18H21BO3
Molecular Weight	296.17 g/mol
Synonyms	3-Phenoxyphenylboronic acid pinacol ester; (3-Phenoxyphenyl)boronic acid pinacol ester; 2-(3-Phenoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Phenoxybenzeneboronic acid pinacol ester; B-(3-Phenoxyphenyl)boronic acid pinacol ester; [3-(Phenoxy)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Phenoxyphenyl-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring traceability and reliability for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.