Description

3-Methyl-5-Pinacolatoboryl-Indazole is a specialized organoboron building block of significant interest in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a key boron reagent for forming carbon-carbon bonds, essential in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the synthesis of novel indazole-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Serves as a building block for creating new pesticides and herbicides with improved efficacy.
• Material Science: Employed in the development of organic electronic materials and functional polymers.
• Chemical Biology Probes: Utilized to create labeled compounds for studying biological pathways and target engagement.
• Process Development & Scale-up: Provides a reliable, high-purity starting material for optimizing synthetic routes from lab to pilot plant.

Basic Information

Product Name	3-Methyl-5-Pinacolatoboryl-Indazole
CAS No.	864771-17-5
Molecular Formula	C15H21BN2O2
Molecular Weight	272.15 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methyl-1H-indazole; 3-Methyl-1H-indazole-5-boronic acid pinacol ester; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazole; 3-Methyl-5-pinacol boronate indazole; 864771-17-5; 5-Borono-3-methyl-1H-indazole, pinacol ester; 3-Methylindazole-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-Pinacolatoboryl-Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and potentially air/moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.