Description

n-Methyl-n-Pyridin-2-Yl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for the Suzuki-Miyaura cross-coupling reaction, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, as well as in materials science for creating advanced organic electronic materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing biphenyl or arylpyridine motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl couplings.
• Material Science Research: Serves as a monomer or building block for creating organic semiconductors, ligands for catalysts, and advanced polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and tool compounds for biological target identification and validation.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.
• Ligand Synthesis for Catalysis: Used to prepare sophisticated bidentate or polydentate ligands for transition metal catalysis.

Basic Information

Item	Details
Product Name	n-Methyl-n-Pyridin-2-Yl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide
CAS No.	864759-39-7
Molecular Formula	C20H25BN2O3
Molecular Weight	352.24 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methyl-N-(pyridin-2-yl)benzamide; 2-Methyl-2-[4-[(2-pyridinyl)(methyl)carbamoyl]phenyl]-1,3,2-dioxaborinane 4,4,5,5-tetramethyl ester; N-Methyl-N-(pyridin-2-yl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; Benzamide, N-methyl-N-2-pyridinyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 864759-39-7; Boronic acid, B-[4-[(2-pyridinyl)(methyl)carbamoyl]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our n-Methyl-n-Pyridin-2-Yl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This compound is easily oxidized and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area Percent)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.