Description

n-Pyridin-4-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop new active ingredients and functional molecules. The CAS number for this compound is 864754-25-6.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing biphenyl or heterocyclic motifs for oncology, CNS, and metabolic disease targets.
• Agrochemical Research: Used to construct complex molecular scaffolds for the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs, organic photovoltaics, and conductive polymers.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways and target engagement.
• Library Synthesis for Drug Discovery: Facilitates the rapid generation of diverse compound libraries via parallel and combinatorial chemistry approaches in medicinal chemistry campaigns.
• Ligand & Catalyst Development: Used to synthesize novel bidentate or polydentate ligands for transition metal catalysis and asymmetric synthesis.

Basic Information

Item	Detail
Product Name	n-Pyridin-4-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide
CAS No.	864754-25-6
Molecular Formula	C20H25BN2O3
Molecular Weight	352.24 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(pyridin-4-ylmethyl)benzamide; 4-(N-Pyridin-4-ylmethylcarbamoyl)phenylboronic acid pinacol ester; 864754-25-6; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[(pyridin-4-yl)methyl]benzamide; Benzamide, N-(4-pyridinylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; N-(Pyridin-4-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
EINECS	Contact for details

Quality Control

Our n-Pyridin-4-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and hydrolysis. Due to its hygroscopic nature, the container should be allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.