Description

n-Pyridin-3-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This advanced intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the construction of complex organic ligands and catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labeled compounds for biological target identification and mechanism-of-action studies.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	n-Pyridin-3-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide
CAS No.	864754-24-5
Molecular Formula	C20H25BN2O3
Molecular Weight	352.24 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(pyridin-3-ylmethyl)benzamide; 3-Pyridylmethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide; 864754-24-5; Benzamide, N-(3-pyridinylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; N-(Pyridin-3-ylmethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide
EINECS	Contact for details

Quality Control

Our n-Pyridin-3-Ylmethyl-4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance in cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.