Description

4-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyrazol-1-Ylmethyl]-Pyridine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in its role as a protected boronic acid derivative, offering enhanced stability and handling properties compared to its free acid form. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and the pyrazole-pyridine scaffold, enabling the synthesis of complex biaryl structures.
• Pharmaceutical Intermediate: Serves as a crucial building block in the research and development of active pharmaceutical ingredients (APIs), especially those containing pyrazole and pyridine heterocycles.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the specific heterocyclic framework is required for biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for catalysis or as a precursor for metal-organic frameworks (MOFs) and functional materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and target engagement.
• Polymer and Material Science: Acts as a monomer or functionalization agent for creating polymers with specific electronic or photophysical properties.

Basic Information

Item	Details
Product Name	4-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Pyrazol-1-Ylmethyl]-Pyridine
CAS No.	864754-20-1
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	4-((4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine; 1-((Pyridin-4-yl)methyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(pyridin-4-ylmethyl)-1H-pyrazole; Pyridine, 4-[[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]methyl]-; 864754-20-1; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)methyl)pyridine
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity. Every lot is characterized using advanced analytical techniques including HPLC, NMR (1H, 13C, 11B), and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.