Description

4,4,5,5-Tetramethyl-2-[3-(2,2,2-Trifluoro-Ethoxy)-Phenyl]-[1,3,2]Dioxaborolane is a high-purity organoboron reagent, specifically a pinacol boronic ester, critical for modern synthetic chemistry. Its value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This compound is essential for researchers and process chemists in pharmaceutical R&D, agrochemical discovery, and advanced materials science, where it facilitates the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for constructing complex biaryl scaffolds found in active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Development: Serves as a precursor for creating advanced organic electronic materials, including charge-transport layers and emissive materials for OLED displays.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labeled compounds for studying biological pathways and target engagement.
• Polymer & Specialty Chemical Manufacturing: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-[3-(2,2,2-Trifluoro-Ethoxy)-Phenyl]-[1,3,2]Dioxaborolane
CAS No.	864754-15-4
Molecular Formula	C15H20BF3O3
Molecular Weight	316.13 g/mol
Synonyms	3-(2,2,2-Trifluoroethoxy)phenylboronic acid pinacol ester; [3-(2,2,2-Trifluoroethoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-(Trifluoroethoxy)phenylboronic acid pinacol ester; 3-(2,2,2-Trifluoroethoxy)benzeneboronic acid pinacol ester; 3-(Trifluoroethoxy)phenyl-Bpin; 864754-15-4; (3-(2,2,2-Trifluoroethoxy)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-[3-(2,2,2-Trifluoro-Ethoxy)-Phenyl]-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed batch-specific data are provided to guarantee consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.