Description

2-[4-([1,3]Dioxolan-2-Ylmethoxy)-3-Methoxy-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is a high-purity, protected boronic ester derivative designed for advanced synthetic chemistry applications. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing complex biaryl and heterobiaryl structures found in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the boronic ester functionality allows for precise carbon-carbon bond formation.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the synthesis of labeled compounds for biological studies.
• Process Chemistry Development: Serves as a reliable and stable reagent for scaling up synthetic routes from laboratory to pilot plant scale.
• Academic & Industrial R&D: A fundamental tool for methodology development and exploring new chemical spaces in organic synthesis laboratories worldwide.

Basic Information

Product Name	2-[4-([1,3]Dioxolan-2-Ylmethoxy)-3-Methoxy-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane
CAS No.	864754-09-6
Molecular Formula	C₁₉H₂₉BO₆
Molecular Weight	364.24 g/mol
Synonyms	(4-(2-(1,3-Dioxolan-2-yl)ethoxy)-3-methoxyphenyl)boronic acid pinacol ester; 2-(4-(2-(1,3-Dioxolan-2-yl)ethoxy)-3-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3-Methoxy-4-(2-(1,3-dioxolan-2-yl)ethoxy)benzeneboronic acid pinacol ester; Pinacol [4-(2-(1,3-dioxolan-2-yl)ethoxy)-3-methoxyphenyl]boronate; Protected Boronic Ester 864754-09-6; Boron, [4-[2-(1,3-dioxolan-2-yl)ethoxy]-3-methoxyphenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl-
EINECS	Contact for details

Quality Control

Our 2-[4-([1,3]Dioxolan-2-Ylmethoxy)-3-Methoxy-Phenyl]-4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.