Description

Piperazin-1-Yl-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanone is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex carbon-carbon bonds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Research: Used to construct novel heterocyclic scaffolds for the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Material Science: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Proteomics: Employed as a versatile handle for bioconjugation and the development of molecular probes and enzyme inhibitors.
• Academic & Contract Research: A valuable reagent for methodology development and the synthesis of complex organic molecules in research laboratories.
• Ligand Synthesis: Used in the preparation of novel ligands for catalysis, including those for asymmetric synthesis and transition metal complexes.

Basic Information

Product Name	Piperazin-1-Yl-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanone
CAS No.	864754-07-4
Molecular Formula	C17H25BN2O3
Molecular Weight	316.21 g/mol
Synonyms	1-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoyl]piperazine; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzoic acid piperazide; Piperazine-1-carboxylic acid [4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenyl]-amide; (4-(Piperazine-1-carbonyl)phenyl)boronic acid pinacol ester; 864754-07-4; 4-Piperazin-1-ylcarbonylphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our Piperazin-1-Yl-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenyl]-Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard reagents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient humidity. For optimal stability, store at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.