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[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Yl]-Methanol CAS NO 864754-05-2


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CAS No.:864754-05-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Yl]-Methanol is a high-value boronic ester derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex organic molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise, scalable synthesis of thiophene-containing target molecules.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates containing functionalized thiophene rings.
  • Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate thiophene motifs for enhanced efficacy.
  • Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for creating advanced organic semiconductors and emissive materials used in display and lighting technologies.
  • Polymer & Material Science: Enables the synthesis of conjugated polymers and specialty materials with tailored electronic and optical properties.
  • Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new C-C bond formation strategies and novel heterocyclic compounds.
  • Ligand & Catalyst Development: Used to construct complex ligand frameworks for catalysis and metal-organic frameworks (MOFs).

Basic Information

Item Detail
Product Name [4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Yl]-Methanol
CAS No. 864754-05-2
Molecular Formula C11H17BO3S
Molecular Weight 240.13 g/mol
Synonyms 2-(Hydroxymethyl)thiophene-4-boronic acid pinacol ester; (4-(Hydroxymethyl)thiophen-2-yl)boronic acid pinacol ester; 4-(Hydroxymethyl)thiophene-2-boronic acid pinacol ester; 2-(Hydroxymethyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene; 864754-05-2; Thiophene-2-methanol, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
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Quality Control

Our [4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Yl]-Methanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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