Description

2-Bromo-5-Methyl-1,3,4-Oxadiazole is a versatile halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the reactive bromine substituent, which enables efficient cross-coupling and functionalization reactions to construct complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the oxadiazole scaffold's bioactivity.
• Material Science Research: Serves as a precursor for the synthesis of specialized polymers, ligands, and functional materials with tailored electronic or photophysical properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems and mechanisms.
• Cross-Coupling Reactions: Acts as an effective electrophilic partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Heterocyclic Chemistry: A fundamental building block for the construction of more complex, fused, or substituted heterocyclic systems.

Basic Information

Item	Detail
Product Name	2-Bromo-5-Methyl-1,3,4-Oxadiazole
CAS No.	864750-58-3
Molecular Formula	C3H3BrN2O
Molecular Weight	162.97 g/mol
Synonyms	5-Methyl-2-bromo-1,3,4-oxadiazole; 2-Bromo-5-methyl-[1,3,4]oxadiazole; 1,3,4-Oxadiazole, 2-bromo-5-methyl-; Methylbromooxadiazole
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-5-Methyl-1,3,4-Oxadiazole is manufactured and controlled under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.