Description

2-(2-Chloro-4-Fluorophenyl)Acetaldehyde is a versatile aromatic aldehyde building block characterized by its reactive carbonyl group and halogen-substituted phenyl ring. This compound matters for its critical role as a key intermediate in the synthesis of complex, high-value molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), advanced crop protection agents, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the fluorinated aromatic structure for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers where specific halogenated aromatic units are required.
• Custom Synthesis and Contract Manufacturing: A valuable building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	2-(2-Chloro-4-Fluorophenyl)Acetaldehyde
CAS No.	864437-19-4
Molecular Formula	C8H6ClFO
Molecular Weight	172.58 g/mol
Synonyms	2-(2-Chloro-4-fluorophenyl)ethanal; 2-Chloro-4-fluorobenzeneacetaldehyde; (2-Chloro-4-fluorophenyl)acetaldehyde; 2-Chloro-4-fluorophenylacetaldehyde; α-Chloro-2-fluoro-4-acetaldehyde benzene; 864437-19-4; 2-(2-Chloro-4-fluorophenyl)ethan-1-one (common misnomer for aldehyde form)
EINECS	Contact for details

Quality Control

Our 2-(2-Chloro-4-Fluorophenyl)Acetaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.