Description

(αs)-α-(Aminomethyl)-Benzenepropanoic Acid Methyl Ester Hydrochloride is a specialized chiral intermediate of significant importance in advanced organic synthesis. This compound matters for its role as a critical building block in the development of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise stereochemistry. Pharmaceutical R&D laboratories and fine chemical manufacturers need it for constructing complex molecules, particularly in the synthesis of potential drug candidates targeting neurological and metabolic pathways.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel Active Pharmaceutical Ingredients (APIs).
• Peptidomimetic Synthesis: Used in the construction of peptide analogs and mimetics for drug discovery programs.
• Asymmetric Synthesis: Serves as a valuable starting material or intermediate in catalytic asymmetric reactions to introduce stereogenic centers.
• Neurological Research Compounds: Employed in the synthesis of compounds being investigated for central nervous system (CNS) disorders.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis & Contract Manufacturing: A critical component for CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for clients.

Basic Information

Product Name	(αs)-α-(Aminomethyl)-Benzenepropanoic Acid Methyl Ester Hydrochloride
CAS No.	864182-47-8
Molecular Formula	C12H18ClNO2
Molecular Weight	243.73 g/mol
Synonyms	Methyl (αS)-α-(aminomethyl)benzenepropanoate hydrochloride; (S)-Methyl 3-amino-2-benzylpropanoate hydrochloride; (S)-2-Benzyl-3-aminopropionic acid methyl ester hydrochloride; L-2-Benzyl-3-aminopropionic acid methyl ester HCl; (S)-3-Amino-2-benzylpropanoic acid methyl ester hydrochloride; (S)-Methyl 3-amino-2-benzylpropionate HCl; (αS)-α-(Aminomethyl)benzenepropanoic Acid Methyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our (αs)-α-(Aminomethyl)-Benzenepropanoic Acid Methyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.