Description

3-(n-Boc-Piperidin-4-Yloxy)Phenylboronic Acid Pinacol Ester is a high-purity, protected boronic ester derivative designed for advanced synthetic chemistry. This compound serves as a critical building block in the synthesis of complex molecules, offering excellent stability and reactivity for cross-coupling reactions. It is primarily utilized by research scientists and process chemists in the pharmaceutical and agrochemical industries for drug discovery and development programs.

Application

• Pharmaceutical Intermediates: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex piperidine and aryl motifs.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable boronate reagent for forming carbon-carbon bonds, essential for constructing biaryl and heterobiaryl structures in medicinal chemistry.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) group provides orthogonal protection for the piperidine nitrogen, allowing for selective deprotection during multi-step syntheses.
• Chemical Biology Probes: Used in the development of molecular probes and tools for studying biological targets and pathways.
• Agrochemical Research: Employed in the discovery and synthesis of novel crop protection agents and herbicides.
• Material Science: Potential monomer or building block for creating functional organic materials and polymers.

Basic Information

Product Name	3-(n-Boc-Piperidin-4-Yloxy)Phenylboronic Acid Pinacol Ester
CAS No.	864136-41-4
Molecular Formula	C22H34BNO5
Molecular Weight	403.32 g/mol
Synonyms	3-[(1-Boc-4-piperidinyl)oxy]benzeneboronic acid pinacol ester; 3-(1-tert-Butoxycarbonyl-4-piperidyloxy)phenylboronic acid pinacol ester; 3-(N-Boc-piperidin-4-yloxy)phenylboronic acid pinacol ester; 3-(1-Boc-4-piperidinyloxy)phenylboronic acid pinacol ester; 3-(1-(tert-Butoxycarbonyl)piperidin-4-yloxy)phenylboronic acid pinacol ester; 3-(4-((tert-Butoxycarbonyl)amino)phenoxy)phenylboronic acid pinacol ester (common misnomer); BOC-4-Piperidinyloxy Phenyl Boronate Pinacol Ester
EINECS	Contact for details

Quality Control

Our 3-(n-Boc-Piperidin-4-Yloxy)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.