Description

(4-[(tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid CAS NO 863752-59-4 is a high-value, protected amino-pyridine boronic acid derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules through reliable cross-coupling reactions, particularly Suzuki-Miyaura couplings. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and other small-molecule drug discovery programs.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds with aryl/heteroaryl halides, enabling library synthesis and lead optimization.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require complex heterocyclic architectures.
• Material Science: Employed in the synthesis of organic electronic materials, ligands for catalysts, and functionalized polymers.
• Chemical Biology & Proteomics: Useful for creating molecular probes and affinity tags due to the reactive boronic acid group and protected amine handle.
• Custom Synthesis & Contract Manufacturing: A sought-after starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	(4-[(tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid
CAS No.	863752-59-4
Molecular Formula	C10H15BN2O4
Molecular Weight	238.05 g/mol
Synonyms	3-Borono-4-[(tert-butoxycarbonyl)amino]pyridine; 4-[(Boc)Amino]-3-pyridineboronic Acid; 4-(Boc-amino)-3-pyridinylboronic Acid; 4-(tert-Butoxycarbonylamino)pyridine-3-boronic Acid; (4-((tert-Butoxycarbonyl)amino)pyridin-3-yl)boronic Acid; Boc-4-Amino-3-pyridinylboronic Acid; 3-Pyridineboronic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-
EINECS	Contact for details

Quality Control

Our (4-[(tert-Butoxycarbonyl)Amino]Pyridin-3-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our commitment to quality supports compliance in cGMP and ISO 9001 environments for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm
Residue on Ignition	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.