Description

2-Amino-4-Methylphenylboronic Acid, Pinacol Ester is a protected boronic acid derivative, a crucial building block in modern synthetic chemistry. Its value lies in its enhanced stability compared to the free boronic acid, facilitating handling and storage while remaining a key reagent for Suzuki-Miyaura cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides that require specific biphenyl or heterobiaryl structures.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Organic Electronic Materials: Employed in the construction of conjugated polymers and small molecules for OLEDs, OFETs, and other optoelectronic devices.
• Chemical Biology & Proteomics: Utilized in the development of molecular probes and activity-based protein profiling (ABPP) reagents.
• Advanced Material Research: A building block for metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other functional porous materials.

Basic Information

Product Name	2-Amino-4-Methylphenylboronic Acid, Pinacol Ester
CAS No.	863578-36-3
Molecular Formula	C13H20BNO2
Molecular Weight	233.12 g/mol
Synonyms	2-Amino-4-methylbenzeneboronic acid pinacol ester; (2-Amino-4-methylphenyl)boronic acid pinacol ester; 2-Amino-p-tolylboronic acid pinacol ester; 4-Methyl-2-aminophenylboronic acid pinacol ester; B-(2-Amino-4-methylphenyl)boronic acid pinacol ester; 2-Amino-4-methylphenylboronic acid neopentyl glycol ester (common alternative); 2-AMino-4-Methylphenyl-Bpin; AMT-Bpin
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and production needs with reliable and traceable quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.