Description

2-Amino-5-Fluorophenyl Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific fluorinated biphenyl structures.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and semiconductors, where precise molecular engineering is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors.
• Academic & Process R&D: A valuable reagent for methodological development and scaling up synthetic routes in laboratory and pilot plant settings.

Basic Information

Product Name	2-Amino-5-Fluorophenyl Boronic Acid Pinacol Ester
CAS No.	863578-24-9
Molecular Formula	C₁₂H₁₇BFNO₂
Molecular Weight	237.08 g/mol
Synonyms	5-Fluoro-2-aminophenylboronic acid pinacol ester; (2-Amino-5-fluorophenyl)boronic acid pinacol ester; 2-Amino-5-fluorobenzeneboronic acid pinacol ester; 2-Amino-5-fluorophenyl-Bpin; 5-Fluoro-2-aminophenyl-Bpin; 2-Amino-5-fluorophenylboronic acid, pinacol cyclic ester; 2-Amino-5-fluorophenylboronic acid neopentyl glycol ester (common alternative); B-(2-Amino-5-fluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluorophenyl Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full batch traceability are provided to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.