Description

2-Amino-4-Chlorophenyl Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and the synthesis of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging its functional group compatibility.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLEDs and conductive polymers, due to its aromatic and boronic ester functionalities.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes for diagnostic and research applications.
• Catalyst & Ligand Preparation: Serves as a starting material for synthesizing specialized ligands and catalysts used in asymmetric synthesis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and fine chemical companies for custom synthesis projects requiring high-fidelity boronic acid derivatives.

Basic Information

Product Name	2-Amino-4-Chlorophenyl Boronic Acid Pinacol Ester
CAS No.	863578-21-6
Molecular Formula	C12H17BClNO2
Molecular Weight	253.53 g/mol
Synonyms	2-Amino-4-chlorobenzeneboronic acid pinacol ester; (2-Amino-4-chlorophenyl)boronic acid pinacol ester; 4-Chloro-2-aminophenylboronic acid pinacol ester; B-(2-Amino-4-chlorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (2-amino-4-chlorophenyl)boronate; 2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; CAS 863578-21-6
EINECS	Contact for details

Quality Control

Our 2-Amino-4-Chlorophenyl Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.