Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzo[D]Imidazol-2-Amine is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in the development of pharmaceuticals and advanced materials. Its core value lies in the versatile boronic ester functional group, which enables efficient cross-coupling reactions to construct complex molecular architectures. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used to construct heterocyclic scaffolds in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a monomer or functionalization agent in the synthesis of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Employed as a building block for activity-based probes and bioconjugation reagents due to the reactive amine and boronate groups.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and catalysis research within university and CRO laboratories.
• Ligand Synthesis: Used to prepare sophisticated N-heterocyclic ligands for transition metal catalysis.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzo[D]Imidazol-2-Amine
CAS No.	863328-18-1
Molecular Formula	C15H20BN3O2
Molecular Weight	285.15 g/mol
Synonyms	2-Amino-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazol-2-amine; 2-Amino-5-(pinacolatoboryl)-1H-benzimidazole; Benzo[D]Imidazol-2-Amine, 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-; 5-Pinacolatoboryl-1H-benzimidazol-2-amine; 863328-18-1; BRN 12511636
EINECS	Contact for details

Quality Control

Our production of 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-Benzo[D]Imidazol-2-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and identity confirmation via NMR and MS. A detailed Certificate of Analysis (COA) documenting all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.