Description

6-(Trifluoromethyl)-1-Benzothiophene-2-Carbaldehyde is a high-value fluorinated heterocyclic building block characterized by its benzothiophene core and reactive aldehyde functional group. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals, where the trifluoromethyl group is prized for its ability to modulate lipophilicity, metabolic stability, and binding affinity. It serves as a critical intermediate for researchers and manufacturers in medicinal chemistry, material science, and fine chemical production.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Material Science Research: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its conjugated benzothiophene system.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on molecular properties and reactivity.
• Custom Synthesis and Contract Manufacturing: Supplied to fine chemical companies for use in custom synthesis projects and scale-up processes.

Basic Information

Product Name	6-(Trifluoromethyl)-1-Benzothiophene-2-Carbaldehyde
CAS No.	863118-49-4
Molecular Formula	C10H5F3OS
Molecular Weight	230.21 g/mol
Synonyms	6-(Trifluoromethyl)benzo[b]thiophene-2-carboxaldehyde; 1-Benzothiophene-2-carboxaldehyde, 6-(trifluoromethyl)-; 6-Trifluoromethyl-1-benzothiophene-2-carbaldehyde; 6-Trifluoromethylbenzo[b]thiophene-2-carbaldehyde; 2-Formyl-6-(trifluoromethyl)benzothiophene; 6-(Trifluoromethyl)benzothiophene-2-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)-1-Benzothiophene-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP, ISO, and other relevant regulatory frameworks for research and commercial use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.