Description

3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester is a high-purity organoboron building block essential for modern synthetic chemistry. This compound matters as a versatile reagent for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex sulfur-containing heterocycles. It is primarily needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing dihydrothiopyran or related sulfur heterocycles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with tailored biological activity.
• Material Science: Enables the creation of advanced organic electronic materials, ligands for catalysis, and functional polymers via cross-coupling.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic ester partner for palladium-catalyzed carbon-carbon bond formation with aryl/heteroaryl halides.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Ligand and Catalyst Development: Acts as a precursor for creating novel bidentate or monodentate ligands used in asymmetric catalysis.

Basic Information

Product Name	3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester
CAS No.	862129-81-5
Molecular Formula	C11H19BO2S
Molecular Weight	226.14 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydro-2H-thiopyran; 3,6-Dihydro-2H-thiopyran-4-boronic acid pinacol ester; 2-(3,6-Dihydro-2H-thiopyran-4-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(Pinacolatoboryl)-3,6-dihydro-2H-thiopyran; Dihydrothiopyran-4-boronic acid pinacol ester; Thiopyran boronic ester; B-3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3,6-Dihydro-2H-thiopyran-4-ylboronic acid pinacol ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.