Description

4,4,5,5-Tetramethyl-2-(4-Methylsulfonylcyclohexen-1-Yl)-1,3,2-Dioxaborolane is a high-purity, advanced boronic ester building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds and complex organic molecules.
• Pharmaceutical Intermediate: Used in the research and development of potential drug candidates, particularly in constructing sterically hindered or complex ring systems.
• Agrochemical Synthesis: Employed in the creation of novel herbicides, fungicides, and insecticides that require specific boronate intermediates.
• Material Science Research: Acts as a precursor for organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in the synthesis of tagged molecules for studying biological processes and protein interactions.
• Catalyst and Ligand Development: Serves as a starting material for creating novel catalysts and ligands used in asymmetric synthesis.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(4-Methylsulfonylcyclohexen-1-Yl)-1,3,2-Dioxaborolane
CAS No.	862129-71-3
Molecular Formula	C₁₃H₂₃BO₄S
Molecular Weight	286.20 g/mol
Synonyms	2-(4-Methylsulfonyl-1-cyclohexen-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-[4-(methylsulfonyl)cyclohex-1-en-1-yl]-1,3,2-dioxaborolane; (4-Methylsulfonylcyclohex-1-en-1-yl)boronic acid pinacol ester; Pinacol (4-(methylsulfonyl)cyclohex-1-en-1-yl)boronate; 862129-71-3; BRN 8288967
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(4-Methylsulfonylcyclohexen-1-Yl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.