Description

2-(3-(Benzyloxy)Prop-1-Ynyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-value organoboron building block, specifically a pinacol-protected alkynyl boronic ester, essential for modern synthetic chemistry. Its core value lies in enabling efficient, selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, to construct complex molecular architectures. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing new active ingredients and functional molecules. CAS No. 862126-33-8.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing carbon-carbon bonds in the development of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and insecticides requiring specific alkynyl-substituted structures.
• Material Science & OLED Development: Serves as a precursor for creating conjugated polymers and small molecule emitters used in organic light-emitting diodes (OLEDs) and electronic materials.
• Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Development: Utilized in click chemistry and bio-conjugation strategies to label biomolecules or create molecular probes for imaging and diagnostics.
• Academic & Process R&D: A versatile tool in research laboratories for methodological development and scaling up synthetic routes in process chemistry.

Basic Information

Product Name	2-(3-(Benzyloxy)Prop-1-Ynyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	862126-33-8
Molecular Formula	C20H29BO3
Molecular Weight	328.26 g/mol
Synonyms	3-(Benzyloxy)-1-propynylboronic acid pinacol ester; 3-Benzyloxy-1-propynylboronic Acid Pinacol Ester; 2-[3-(Benzyloxy)prop-1-yn-1-yl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (3-Benzyloxyprop-1-yn-1-yl)boronic acid pinacol ester; Pinacol (3-(Benzyloxy)prop-1-yn-1-yl)boronate; Alkynyl Boronic Ester BnO-PE; BnO-protected Alkynyl Pinacol Boronate
EINECS	Contact for details

Quality Control

Our 2-(3-(Benzyloxy)Prop-1-Ynyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee compliance with your research or process specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (NMR)	Conforms to structure (1H NMR, 13C NMR, 11B NMR)
Purity (HPLC/GC)	≥95% (Typical 97-99%)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.