Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Benzofuran-1(3H)-One is a high-purity, advanced pharmaceutical intermediate and versatile synthetic building block. This compound is valued for its role as a key boronic ester derivative, enabling critical carbon-carbon bond formation reactions in complex molecule synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in Suzuki-Miyaura cross-coupling reactions for constructing biaryl and heteroaryl structures.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the benzofuranone scaffold offers unique biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in advanced display technologies.
• Polymer Chemistry: Employed in the synthesis of specialty polymers and functional materials with tailored optical or electronic properties.
• Chemical Biology & Proteomics: Acts as a probe or linker in the development of chemical tools for studying biological systems and protein interactions.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university laboratories and CROs (Contract Research Organizations).

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Benzofuran-1(3H)-One
CAS No.	862081-38-7
Molecular Formula	C14H17BO4
Molecular Weight	260.10 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-benzofuran-1(3H)-one; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-isobenzofuran-1-one; 6-(Tetramethyl-1,3,2-dioxaborolan-2-yl)isobenzofuran-1(3H)-one; 6-Pinacolatoboryl-3H-isobenzofuran-1-one; 6-Boronobenzofuranone pinacol ester; 862081-38-7; 6-(Pinacolatoboryl)isobenzofuran-1(3H)-one
EINECS	Contact for details

Quality Control

Our production of 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-2-Benzofuran-1(3H)-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR (1H and 13C), and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.