Description

5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isobenzofuran-1(3H)-One is a high-purity, advanced pharmaceutical intermediate and versatile organic building block. This compound is valued for its role as a key synthon in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, especially for small molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds for constructing complex aromatic and heteroaromatic systems in medicinal chemistry.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and herbicides.
• Material Science: Serves as a precursor for organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Synthesis: A versatile boronic ester used in organic synthesis for introducing functionalized isobenzofuranone moieties.
• Academic & Industrial R&D: Essential for exploratory research in synthetic methodology and new compound library generation.

Basic Information

Product Name	5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isobenzofuran-1(3H)-One
CAS No.	862081-37-6
Molecular Formula	C14H17BO4
Molecular Weight	260.09 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3H-isobenzofuran-1-one; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)isobenzofuran-1(3H)-one; 1(3H)-Isobenzofuranone, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)phthalide; 5-Pinacolatoborylphthalide; 5-Boronophthalide pinacol ester
EINECS	Contact for details

Quality Control

Our 5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Isobenzofuran-1(3H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.