Description

Salvinorin B Mesylate is a chemically modified derivative of the potent diterpenoid Salvinorin A, designed for enhanced stability and research utility. This compound is of significant interest in pharmacological research for studying κ-opioid receptor (KOR) signaling pathways and related neurological mechanisms. It serves as a critical reference standard and intermediate for researchers in pharmaceutical development, neuroscience, and medicinal chemistry, particularly for those investigating non-opioid analgesic targets and receptor-specific probes.

Application

• Pharmacological Research: Acts as a key reference standard and tool compound for in vitro studies targeting the κ-opioid receptor (KOR).
• Neuroscience Studies: Used in receptor binding assays and functional studies to understand KOR-mediated effects on perception, mood, and pain.
• Medicinal Chemistry: Serves as a stable synthetic intermediate for the development of novel receptor-selective ligands and potential therapeutic agents.
• Analytical Standard: Employed in method development and validation for analytical techniques like HPLC and LC-MS in forensic and pharmaceutical quality control laboratories.
• Biochemical Screening: Utilized in high-throughput screening (HTS) campaigns to identify and characterize new modulators of opioid receptor pathways.

Basic Information

Product Name	Salvinorin B Mesylate
CAS No.	862073-79-8
Molecular Formula	C24H30O9S
Molecular Weight	494.56 g/mol
Synonyms	Salvinorin B methanesulfonate; (2S,4aR,6aR,7R,9S,10aS,10bR)-9-(Methanesulfonyloxy)-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxododecahydro-1H-benzo[f]isochromene-7-carboxylic acid methyl ester; Salvinorin B mesylate salt; Sal B Mesylate
EINECS	Contact for details

Quality Control

Our Salvinorin B Mesylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.