Description

4-Bromo-2-(Trifluoromethyl)Benzaldehyde is a versatile and high-value aromatic aldehyde building block characterized by its bromine and trifluoromethyl substituents. This compound is essential for the synthesis of complex molecules, where its unique halogenated and fluorinated structure enables precise tuning of electronic properties, lipophilicity, and metabolic stability. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the creation of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic and R&D Laboratories: Used in fundamental research to explore new chemical reactions and develop novel synthetic methodologies.

Basic Information

Product Name	4-Bromo-2-(Trifluoromethyl)Benzaldehyde
CAS No.	861928-27-0
Molecular Formula	C8H4BrF3O
Molecular Weight	253.02 g/mol
Synonyms	4-Bromo-α,α,α-trifluoro-o-tolualdehyde; 2-(Trifluoromethyl)-4-bromobenzaldehyde; 4-Bromo-2-trifluoromethylbenzaldehyde; Benzaldehyde, 4-bromo-2-(trifluoromethyl)-; 4-Bromo-α,α,α-trifluoro-2-methylbenzaldehyde; 861928-27-0; Aldrich-661336 (Supplier Code)
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles against agreed specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.