Description

Methyl 3-Fluoro-5-Iodo-4-Methylbenzoate is a high-purity, multi-functional halogenated aromatic ester, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile molecular scaffold for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise, reliable building blocks for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and plant growth regulators, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated and iodinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new synthetic methodologies and creating specialized chemical libraries.
• Fluorine Chemistry Studies: Acts as a model compound for studying the effects of fluorine substitution on the reactivity and physical properties of benzoate esters.

Basic Information

Product Name	Methyl 3-Fluoro-5-Iodo-4-Methylbenzoate
CAS No.	861905-21-7
Molecular Formula	C9H8FIO2
Molecular Weight	294.06 g/mol
Synonyms	Benzoic acid, 3-fluoro-5-iodo-4-methyl-, methyl ester; Methyl 3-fluoro-5-iodo-p-toluate; 4-Methyl-3-fluoro-5-iodobenzoic acid methyl ester; 3-Fluoro-5-iodo-4-methylbenzoic acid methyl ester; Methyl 4-methyl-3-fluoro-5-iodobenzoate; 861905-21-7; Methyl 3-fluoro-5-iodo-4-methylbenzenecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Fluoro-5-Iodo-4-Methylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.