Description

1-Chloro-3-Iodo-5-Methoxybenzene, also known as 3-Chloro-5-Iodophenyl Methyl Ether, is a high-value halogenated aromatic building block of significant interest in advanced organic synthesis. Its precise structure, featuring chlorine and iodine substituents on a methoxybenzene scaffold, makes it an essential intermediate for constructing complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, material science, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides, leveraging its halogenated aromatic core.
• Material Science Research: Acts as a building block for creating specialized organic ligands, liquid crystals, and advanced polymers with unique electronic or optical properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form complex biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Organic Electronic Materials: Investigated as a component in the development of organic semiconductors and charge-transport materials.

Basic Information

Product Name	1-Chloro-3-Iodo-5-Methoxybenzene, 3-Chloro-5-Iodophenyl Methyl Ether
CAS No.	861800-86-4
Molecular Formula	C7H6ClIO
Molecular Weight	268.48 g/mol
Synonyms	3-Chloro-5-iodoanisole; 1-Chloro-3-iodo-5-methoxybenzene; Methyl 3-chloro-5-iodophenyl ether; 3-Chloro-5-iodophenyl methyl ether; 5-Chloro-3-iodoanisole; Anisole, 3-chloro-5-iodo-; Benzene, 1-chloro-3-iodo-5-methoxy-
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-Iodo-5-Methoxybenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.