Description

2-(4-Chlorophenyl)-3-(Perfluorophenyl)-1-Tosylaziridine CAS NO 861437-16-3 is a specialized fluorinated aziridine derivative, a high-value synthetic intermediate prized for its unique trifunctional reactivity. This compound is engineered to enable the construction of complex molecular architectures, particularly in advanced materials and pharmaceutical research. It is essential for R&D chemists and process development scientists in the agrochemical, pharmaceutical, and specialty polymer industries seeking to incorporate fluorinated and aryl motifs with precise stereochemical control.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting CNS disorders and anti-infective agents.
• Agrochemical Research: Used in developing next-generation herbicides and fungicides, leveraging the stability and bioactivity of the perfluorophenyl group.
• Advanced Material Synthesis: Serves as a monomer or cross-linking agent for creating specialty polymers with enhanced thermal stability, chemical resistance, and unique surface properties.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create novel chiral ligands and catalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: A critical reagent for academic and industrial research exploring the effects of fluorine substitution on reactivity and molecular conformation.
• Fine Chemical Production: Intermediate in the multi-step synthesis of complex dyes, pigments, and optical materials.

Basic Information

Product Name	2-(4-Chlorophenyl)-3-(Perfluorophenyl)-1-Tosylaziridine
CAS No.	861437-16-3
Molecular Formula	C21H12ClF5NO2S
Molecular Weight	471.83 g/mol
Synonyms	1-Tosyl-2-(4-chlorophenyl)-3-(perfluorophenyl)aziridine; N-[(2R,3S)-2-(4-Chlorophenyl)-3-(pentafluorophenyl)aziridin-1-yl]-4-methylbenzenesulfonamide; 2-(4-Chlorophenyl)-3-(pentafluorophenyl)-1-tosylaziridine; Aziridine, 1-[(4-methylphenyl)sulfonyl]-2-(4-chlorophenyl)-3-(pentafluorophenyl)-, (2R,3S)-rel-; Tosyl Aziridine Derivative 861437-16-3; Perfluorophenyl Chlorophenyl Tosylaziridine
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-3-(Perfluorophenyl)-1-Tosylaziridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to minimize exposure to moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.