Description

2-Amino-n-(3-Methoxyphenyl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide CAS NO 861239-04-5 is a high-purity, advanced pharmaceutical intermediate characterized by its unique tetrahydrobenzothiophene carboxamide structure. This compound is of significant commercial importance as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily sought after by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex heterocyclic scaffolds due to its reactive amino and carboxamide functional groups.
• Research & Development (R&D): Serves as a standard or reference compound in academic and industrial research for studying structure-activity relationships (SAR).
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of target molecules.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Amino-n-(3-Methoxyphenyl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide
CAS No.	861239-04-5
Molecular Formula	C₁₆H₁₈N₂O₂S
Molecular Weight	302.39 g/mol
Synonyms	2-Amino-N-(3-methoxyphenyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 2-Amino-N-(3-methoxyphenyl)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxamide; 861239-04-5; 4,5,6,7-Tetrahydro-2-amino-N-(3-methoxyphenyl)-1-benzothiophene-3-carboxamide; Tetrahydrobenzothiophene carboxamide derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-n-(3-Methoxyphenyl)-4,5,6,7-Tetrahydro-1-Benzothiophene-3-Carboxamide is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting standards for pharmaceutical intermediates. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your regulatory and R&D documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.