Description

1-Bromo-3-Iodo-2-Methoxybenzene, also known as 2-Bromo-6-Iodophenyl Methyl Ether, is a high-value, multi-halogenated aromatic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents on a methoxybenzene core, makes it a versatile precursor for constructing complex molecules via selective cross-coupling reactions. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those requiring complex, halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the halogen atoms allow for further functionalization.
• Material Science Research: Acts as a building block for creating organic electronic materials, such as ligands for OLEDs or charge-transport molecules, due to its halogenated aromatic system.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, where the differential reactivity of bromine and iodine can be exploited for sequential functionalization.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems, leveraging the iodine atom for potential radiolabeling.

Basic Information

Product Name	1-Bromo-3-Iodo-2-Methoxybenzene, 2-Bromo-6-Iodophenyl Methyl Ether
CAS No.	860584-68-5
Molecular Formula	C7H6BrIO
Molecular Weight	312.93 g/mol
Synonyms	2-Bromo-6-iodoanisole; 1-Bromo-3-iodo-2-methoxybenzene; Methyl 2-bromo-6-iodophenyl ether; 2-Bromo-6-iodo-1-methoxybenzene; Anisole, 2-bromo-6-iodo-; 2-Bromo-6-iodophenol methyl ether; 2-Bromo-6-iodophenyl methyl ether; 1-Iodo-3-bromo-2-methoxybenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Iodo-2-Methoxybenzene is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. While produced to high standards, this product is typically offered as a research-grade chemical; specifications for GMP or pharmaceutical-grade material can be discussed based on project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.