Description

2-Bromo-4-tert-Butyl-1-Iodo-Benzene is a high-purity, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromine and iodine substituents, makes it a versatile and valuable intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, material science, and ligand synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the reactivity of its halogen atoms.
• Material Science & OLEDs: Serves as a building block for creating organic semiconductors, liquid crystals, and light-emitting materials for electronic devices.
• Ligand & Catalyst Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for catalysis.
• Chemical Research: A valuable reagent for methodological studies in organic chemistry, particularly in exploring new halogenation or functionalization pathways.
• Fine Chemical Production: Used in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Item	Details
Product Name	2-Bromo-4-tert-Butyl-1-Iodo-Benzene
CAS No.	860435-39-8
Molecular Formula	C10H12BrI
Molecular Weight	323.01 g/mol
Synonyms	1-Bromo-2-iodo-5-tert-butylbenzene; 4-tert-Butyl-1-iodo-2-bromobenzene; 5-tert-Butyl-1-bromo-2-iodobenzene; 2-Bromo-4-(tert-butyl)-1-iodobenzene; 2-Bromo-4-(1,1-dimethylethyl)-1-iodobenzene; 1-Iodo-2-bromo-4-tert-butylbenzene; Benzene, 2-bromo-4-(1,1-dimethylethyl)-1-iodo-
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-tert-Butyl-1-Iodo-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.