Description

4-(Piperidin-1-Ylmethyl)Benzeneboronic Acid, Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile organoboron building block. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry and materials science. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures. The product is supplied with a guaranteed minimum purity of 97% to ensure reliable and reproducible reaction outcomes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic programs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides requiring specific aryl-boronate functionalities.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of sophisticated ligand systems used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A valuable reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	4-(Piperidin-1-Ylmethyl)Benzeneboronic Acid, Pinacol Ester
CAS No.	859833-22-0
Molecular Formula	C19H30BNO3
Molecular Weight	331.26 g/mol
Synonyms	2-[4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]-1,2-oxazinane; 4-((Piperidin-1-yl)methyl)phenylboronic acid pinacol ester; 1,2-Oxazinane, 2-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl]-; 4-(Piperidin-1-ylmethyl)benzeneboronic acid pinacol ester; 4-(N-Piperidinylmethyl)phenylboronic acid pinacol ester; Boronic acid, B-[4-(1-piperidinylmethyl)phenyl]-, 1,1-dimethylethyl ester; 859833-22-0; 4-Piperidin-1-ylmethyl-benzeneboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(Piperidin-1-Ylmethyl)Benzeneboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the specified 97% minimum assay. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment. Our quality commitment supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.