Description

1-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Piperidine is a high-value, protected boronic ester derivative that serves as a critical synthetic intermediate. This compound matters for its role in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental to modern pharmaceutical and advanced materials research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-alkyl linkages.
• Material Science Research: Employed in the creation of organic electronic materials, such as those for OLEDs and organic photovoltaics, where precise conjugation is essential.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of molecular probes and inhibitors.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and CRO laboratory settings.
• Ligand & Catalyst Development: Serves as a precursor for synthesizing novel piperidine-containing ligands and organoboron catalysts.

Basic Information

Product Name	1-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Piperidine
CAS No.	859833-21-9
Molecular Formula	C18H28BNO2
Molecular Weight	301.24 g/mol
Synonyms	3-((Piperidin-1-yl)methyl)phenylboronic acid pinacol ester; 1-[[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]piperidine; (3-((Piperidin-1-yl)methyl)phenyl)boronic acid pinacol ester; 1-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)piperidine; Piperidine, 1-[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl]-
EINECS	Contact for details

Quality Control

Our 1-[3-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Benzyl]Piperidine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) with full analytical data are provided to guarantee compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.