Description

Spiro[2.5]Oct-5-En-6-Yl Boronic Acid Pinacol Ester is a specialized spirocyclic boronic ester building block used in advanced organic synthesis. This compound is valued for its unique strained-ring structure, which provides a versatile handle for cross-coupling reactions and the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the discovery and production of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those requiring spirocyclic or strained-ring scaffolds.
• Agrochemical Research: Employed in the development of new pesticides and herbicides, where its unique structure can contribute to enhanced biological activity and selectivity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers and organic electronic materials with tailored properties.
• Chemical Biology & Probe Development: Used to create molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Catalyst Ligand Synthesis: Acts as a starting material for the preparation of sophisticated ligands used in asymmetric catalysis.
• Academic & Contract Research: A valuable reagent for methodological development and exploring new synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	Spiro[2.5]Oct-5-En-6-Yl Boronic Acid Pinacol Ester
CAS No.	859219-46-8
Molecular Formula	C₁₄H₂₁BO₂
Molecular Weight	232.13 g/mol
Synonyms	6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[2.5]oct-5-ene; Spiro[2.5]oct-5-ene-6-boronic acid pinacol ester; 6-Boronic acid pinacol ester spiro[2.5]oct-5-ene; (Spiro[2.5]oct-5-en-6-yl)boronic acid pinacol ester; 859219-46-8; Spirooctenyl boronic ester
EINECS	Contact for details

Quality Control

Our Spiro[2.5]Oct-5-En-6-Yl Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system supports compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and moisture-sensitive nature. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.