Description

4,4,5,5-Tetramethyl-2-(Spiro[4.5]Dec-7-En-8-Yl)-1,3,2-Dioxaborolane is a high-value, advanced boronic ester building block crucial for modern synthetic chemistry. It matters because it provides a protected, air-stable boronate functional group that is essential for constructing complex molecular architectures via cross-coupling reactions. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/vinyl halides and this boronate ester, enabling the synthesis of biaryl and styrenyl structures.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex, sterically hindered molecular cores.
• Agrochemical Active Ingredient Development: Employed in creating novel herbicides, fungicides, and insecticides that require specific, spatially defined boronate functionalities.
• Material Science & Organic Electronics: Serves as a precursor for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other functional materials where precise molecular conjugation is critical.
• Chemical Biology & Probe Development: Utilized in synthesizing molecular probes and tags for studying biological processes, leveraging its stability and reactivity.
• Process Chemistry & Scale-up: Acts as a reliable building block for the kilogram-scale production of target molecules in pilot plants and commercial manufacturing.

Basic Information

Product Name	4,4,5,5-Tetramethyl-2-(Spiro[4.5]Dec-7-En-8-Yl)-1,3,2-Dioxaborolane
CAS No.	859219-41-3
Molecular Formula	C18H31BO2
Molecular Weight	290.25 g/mol
Synonyms	8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)spiro[4.5]dec-7-ene; Spiro[4.5]dec-7-ene-8-boronic acid pinacol ester; 2-(Spiro[4.5]dec-7-en-8-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 8-Boranespiro[4.5]dec-7-ene, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane deriv.; Pinacol Spiro[4.5]dec-7-ene-8-boronate; Spirocyclic Pinacol Boronate Ester
EINECS	Contact for details

Quality Control

Our 4,4,5,5-Tetramethyl-2-(Spiro[4.5]Dec-7-En-8-Yl)-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) with full characterization data are provided to guarantee compliance with your research and process requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (argon or nitrogen) for long-term storage to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0% (Area %)
Purity (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.