Description

1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-(3,3,5,5-Tetramethyl-1-Cyclohexen-1-Yl) is a specialized organoboron reagent featuring a sterically hindered pinacol boronate ester group attached to a tetramethylcyclohexene scaffold. This compound is valued for its role as a key synthetic intermediate in advanced organic transformations, particularly in cross-coupling reactions. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require high-purity building blocks for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing coupling partner for the synthesis of biaryl and conjugated systems in pharmaceutical intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the construction of active pharmaceutical ingredients (APIs) and complex drug candidates, leveraging its stability and reactivity.
• Agrochemical Research & Development: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Materials Science & Organic Electronics: A precursor for creating organic semiconductors, OLED materials, and other functional polymers where precise molecular structure is crucial.
• Chemical Biology & Probe Development: Utilized in the synthesis of molecular probes and tags for imaging and diagnostic applications.
• Catalyst & Ligand Development: Acts as a building block for novel organometallic catalysts and chiral ligands used in asymmetric synthesis.

Basic Information

Product Name	1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-(3,3,5,5-Tetramethyl-1-Cyclohexen-1-Yl)
CAS No.	859217-85-9
Molecular Formula	C16H27BO2
Molecular Weight	262.20 g/mol
Synonyms	2-(3,3,5,5-Tetramethylcyclohex-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,3,5,5-Tetramethyl-1-cyclohexen-1-ylboronic acid pinacol ester; (3,3,5,5-Tetramethyl-1-cyclohexen-1-yl)boronic acid pinacol ester; Tetramethylcyclohexenyl pinacol boronate; TMCH-Pinacolboronate; 1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,3,5,5-tetramethylcyclohex-1-ene
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 4,4,5,5-Tetramethyl-2-(3,3,5,5-Tetramethyl-1-Cyclohexen-1-Yl) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high chemical purity and lot-to-lot consistency suitable for demanding synthetic applications. Certificates of Analysis (COA) with full specification data are provided to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Purity (NMR)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.