Description

4-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Butyric Acid Ethyl Ester is a high-value, protected boronic ester derivative designed for advanced organic synthesis. This compound is a critical building block in modern pharmaceutical and materials science research, enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology: Employed in the synthesis of probes and labeled compounds for biochemical assays and diagnostic applications.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic routes in organic chemistry laboratories.

Basic Information

Product Name	4-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Butyric Acid Ethyl Ester
CAS No.	859169-90-7
Molecular Formula	C18H27BO5
Molecular Weight	334.22 g/mol
Synonyms	Ethyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]butyrate; 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)butanoic acid ethyl ester; 2-[4-(4-Ethoxy-4-oxobutoxy)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 859169-90-7; Boric acid, cyclic ester with ethyl 4-(4-hydroxyphenoxy)butyrate
EINECS	Contact for details

Quality Control

Our production of 4-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxy]-Butyric Acid Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance for critical coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to ambient moisture. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.