Description

2-Methyl-4-(1H-Pyrazol-1-Yl)Phenylboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its primary value lies in enabling the efficient and selective construction of complex heterocyclic scaffolds, which are critical in advanced material and pharmaceutical research. This compound is specifically designed for use by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity building blocks for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially those containing pyrazole and biaryl motifs for targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial organoboron reagent for forming carbon-carbon bonds between aromatic rings, a fundamental step in creating complex molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific heterocyclic structures.
• Material Science & OLED Development: Employed in the creation of organic electronic materials, such as charge-transport layers or emitters for organic light-emitting diodes (OLEDs).
• Chemical Biology & Probe Development: Utilized for synthesizing molecular probes and inhibitors to study biological pathways and enzyme functions.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge research in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	2-Methyl-4-(1H-Pyrazol-1-Yl)Phenylboronic Acid Pinacol Ester
CAS No.	858523-46-3
Molecular Formula	C₁₇H₂₁BN₂O₂
Molecular Weight	296.18 g/mol
Synonyms	[1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylphenyl]-1H-pyrazole; 2-Methyl-4-(1H-pyrazol-1-yl)benzeneboronic acid pinacol ester; 4-(1H-Pyrazol-1-yl)-2-methylphenylboronic acid pinacol ester; 2-Methyl-4-(pyrazol-1-yl)phenylboronic acid pinacol ester; Pinacol [2-methyl-4-(1H-pyrazol-1-yl)phenyl]boronate; Boronic acid, B-[2-methyl-4-(1H-pyrazol-1-yl)phenyl]-, 1,1-dimethylethyl ester (9CI); 858523-46-3; B-[2-Methyl-4-(1H-pyrazol-1-yl)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Methyl-4-(1H-Pyrazol-1-Yl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistent performance in sensitive cross-coupling applications. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed under an inert atmosphere to maintain stability and prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.